Irradiation

The X-RAD SmART (Precision X-Ray) is a state-of-the-art small animal radiation therapy research platform with cone-beam CT (CBCT) guidance and bioluminescence tomography in a single, self-shielded unit. To allow for image-guided radiotherapy (IGRT), a rotating gantry and a three-axis computer-controlled animal couch are used along with an automated stage correction during irradiation. Both fixed field and dynamic arc (0°to 360°) dose delivery modes are available along with a set of interchangeable collimators of different sizes (from circular 3 mm to rectangular 40 mm x 40 mm).

A dedicated treatment planning software (SmART-ATP) offers the possibility to quickly design complex treatment plans based on the planning CT, with an additional possibility to combine with other imaging modalities (MRI, PET, bioluminescence).

Technical specifications

Beam energy: 20-225 kVp

Maximum dose rate: 4 Gy/min

Voxel resolution at isocenter: 100 μm

Temporal resolution: 15 fps

Imaging dose: 1-10 cGy

Minimal beam diameter: 3 mm

Targeting accuracy: 0.25 mm (standard mode), 0.1 mm (high precision mode)

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